Ingredients
Vitamin E Prostate Cancer Risk: What the Large Trial Found
Vitamin E prostate cancer risk was tested in the SELECT trial of about 35,500 men. Daily 400 IU of synthetic vitamin E did not prevent prostate cancer, and after longer follow-up those men had a 17% higher risk. Protoflow lists 13 mg of vitamin E, far below that dose.
Written by the Protoflow label deskUpdated · 4 min read
The trial01
What did the SELECT trial find about vitamin E?
It found no protection, and a signal of harm. Vitamin E did not prevent prostate cancer in SELECT.
The trial gave about 35,500 men 400 IU of synthetic vitamin E every day. After extended follow-up, the men who took it had a statistically significant 17% higher risk of prostate cancer (NIH ODS, Vitamin E).
That is one trial of one dose and one form. It does not show what a smaller dose does.
The dose02
How does the Protoflow amount compare?
The label lists 13 mg of d-alpha tocopheryl succinate, about 19 IU at most. SELECT used 400 IU, roughly 20 times as much.
NIH puts 1 mg of natural vitamin E at about 1.49 IU, so 13 mg is near 19 IU. The adult need is 15 mg a day, which is why the panel shows 87% of the Daily Value (NIH ODS, Vitamin E).
| Amount | Where it comes from |
|---|---|
| 13 mg (about 19 IU) | One Protoflow serving, 2 capsules (Protoflow bottle label) |
| 15 mg | Adult daily need (NIH ODS, Vitamin E) |
| 400 IU (about 180 mg) | Daily dose in SELECT (NIH ODS, Vitamin E) |
| 1,000 mg | Adult upper limit from supplements (NIH ODS, Vitamin E) |
The takeaway03
Should men with prostate worries avoid vitamin E?
Not by rule, but they should count it. The trial result is about large doses taken for years.
Thirteen milligrams is not the SELECT dose, and no study has tested this product. Add up vitamin E from every pill you take, because multivitamins and fish oil blends often carry some.
Large amounts can also add to bleeding risk with blood thinners such as warfarin (NIH ODS, Vitamin E). Keep taking any prescribed medicine and tell your prescriber about the label.
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See packsBeyond pills04
What matters more than a vitamin for prostate cancer risk?
Screening choices and symptoms that get checked.
- Talk with a clinician about PSA testing; for men 55 to 69 the task force calls it an individual decision (USPSTF, Prostate Cancer Screening).
- Report blood in the urine or a stream that keeps weakening.
Background on the gland is in prostate basics, and the wider safety picture is in are prostate supplements safe.
FAQ05
Protoflow questions people ask
What does 400 IU of vitamin E equal in milligrams?
About 180 mg of the synthetic form. The natural form converts at roughly 1.49 IU per milligram (NIH ODS, Vitamin E), so the same IU number gives a different weight.
Did SELECT test natural or synthetic vitamin E?
Synthetic. The trial used 400 IU of synthetic vitamin E a day (NIH ODS, Vitamin E). Protoflow prints d-alpha tocopheryl succinate, a different esterified form, so the results do not map onto it directly.
Does vitamin E from food raise prostate cancer risk?
The trial tested a pill, not food. Nothing we read links ordinary meals to higher risk, so the caution is about concentrated supplement doses.
Can a PSA test be affected by vitamin E?
The NCI PSA sheet does not list vitamin E as a cause of a raised PSA (NCI, PSA Test Fact Sheet). It names BPH, infection and recent biopsy, so a high number still needs a clinician.
Who wrote this06
Written and reviewed by
Pages built from the label, the brand pages and linked NIH, FDA, FTC, NICE and peer-reviewed sources.
Last updated . See our editorial standards and how we check reviews. This website is run by a USA authorized Protoflow retailer, not by the manufacturer or distributor, PhytoThrive Labs. We make money when you buy through our order links.
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